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P21-ACTIVATED KINASES
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DeCS
Descriptor
English
:
p21-Activated Kinases
Descriptor
Spanish
:
Quinasas p21 Activadas
Descriptor
Portuguese
:
Quinases Ativadas por p21
Tree Number:
D08.811.913.696.620.682.700.596
D12.644.360.552
D12.776.476.548
Definition
English
:
A
family
of serine-threonine kinases that bind to and are activated by
MONOMERIC GTP-BINDING PROTEINS
such as
RAC GTP-BINDING PROTEINS
and CDC42
GTP-BINDING PROTEINS
. They are intracellular signaling kinases that play a
role
the regulation of cytoskeletal organization.
History Note
English
:
2008
Allowable Qualifiers
English
:
administration & dosage
adverse effects
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
52745
Unique Identifier:
D054462
Occurrence in VHL
:
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